Mother-of-two Kacey Ainsworth left Albert Square in May 2006 after a dramatic rape storyline which saw her break-up with partner Billy Mitchell.
The 47 year old revealed that the BBC One soap producers have been in contact about getting her back to Walford.
Speaking in an interview with Radio Times, Kacey explained why she is still considering her options; 'It's not like they haven't asked but the thing is, I have so much on the table at the moment that it would actually be quite difficult to find a space. So it's about timing.'
Shane Ritchie and Kacey
Reflecting on her time in EastEnders, Kacey said; 'The Slaters made a big impact and it all worked well. So, you never say never.'
While Mo would return to an unrecognisable Walford – Charlie Slater is now dead, Kat and Alfie are in Ireland and Zoe hasn't been seen since 2005 – at least she will still have Billy.
Since leaving Walford, Kacey has starred in BBC's Holby Blue between 2007-2008, Hotel Babylon and Granchester since 2014. She is already signed for a second series of the ITV drama.
Parents may also recognise Kacey from her role on the CBeebies channel reading bedtime stories.
The winner of the 2002 National Television Award for Most Popular Actress performed her most memorable story lines with on-screen husband Trevor Morgan played by Alex Ferns.
The domestic abuse plot was praised for its handling of the issue and readers of OK! magazine voted Little Mo as their 'top TV character' of the year.
Queen Elizabeth meeting the cast of Eastenders
After Trev died in a house explosion, Little Mo's troubling storylines were not over as she was raped and fell pregnant, which eventually lead to her split with Billy Mitchell and departure from the square.
It was also reported last week that long-time EastEnder's executive producer Dominic Treadwell-Collins would be leaving the soap.
Dominic said; 'My love for EastEnders is no secret and so the decision to leave Walford has not been one I have taken lightly. When I commit to something, I always give it my all - and after two and a half years of giving my blood to Walford, it is time for me to move on to other things - and keep EastEnders creatively refreshed, something that it has to do to stay at the top of its game.'
Here's hoping we see Little Mo back in the square very soon!