'Age-related macular degeneration (AMD) is one of the commonest causes of visual impairment in the UK. Recently there have been significant developments in our understanding of its underlying causes, in the options for therapeutic and surgical intervention, and in detection and diagnosis through emerging technology for retinal imaging; all of which have transformed the clinical management of a patient with the condition.' Parul Desai, public health and ophthalmology consultant, Moorfields Eye Hospital, London