Rare causes of acne
The description above is the cause of almost all cases of acne. Rarely, certain diseases in girls and women may cause acne, or make acne worse. For example, polycystic ovary syndrome, and conditions that cause excess male hormone to be made in the ovary or adrenal gland. These conditions cause other symptoms in addition to acne such as thinning of scalp hair, excess growth of facial or body hair (hirsutes), and other problems. Another rare cause of acne is exposure to halogenated hydrocarbons (chemicals that occur in some work places).
What makes acne worse?
- The progestogen-only contraceptive pill may make acne worse.
- In women, the hormone changes around the monthly period may cause a flare-up of spots.
- Thick or greasy make-up may, possibly, make acne worse. However, most make-up does not affect acne. You can use make-up to cover some mild spots. Non-comedogenic or oil-free products are most helpful for acne prone skin types.
- Picking and squeezing the spots may cause further inflammation and scarring.
- Sweating heavily or humid conditions may make acne worse. For example, doing regular hot work in kitchens. The extra sweat possibly contributes to blocking pores.
- Spots may develop under tight clothes. For example, under headbands, tight bra straps, tight collars, etc. This may be due to increased sweating and friction under tight clothing.
- Some drugs can make acne worse. For example, phenytoin which some people take for epilepsy, and steroid creams and ointments that are used for eczema. Do not stop a prescribed drug if you suspect it is making your acne worse, but tell your doctor. An alternative may be an option.
- Anabolic steroids (which some body-builders take illegally) can make acne worse.



