How is acromegaly diagnosed?

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A blood test can measure the level of growth hormone. However, a single test is not reliable. The diagnosis of acromegaly is made by a glucose tolerance test. In this test you drink a sugar drink containing 75 grams of glucose. You then have a series of blood tests over two hours. The glucose should lower the blood level of growth hormone. However, if you have acromegaly the growth hormone level remains high.
A blood test to measure the level of IGF-I (see above) may be measured if acromegaly is suspected. This may also be used as an index of disease activity to assess how well treatment is working.
An MRI scan (magnetic resonance imaging scan) or CT scan (computed tomography scan) can show the size of the tumour.
Eye and visual tests will assess if the tumour is pressing on the optic nerve.
If you are confirmed as having acromegaly, other tests will be needed to see if the tumour is causing a lack or excess of other hormones made by the pituitary.